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Abstract The early detection of the coronavirus disease 2019 (COVID-19) outbreak is important to save people’s lives and restart the economy quickly and safely. People’s social behavior, reflected in their mobility data, plays a major role in spreading the disease. Therefore, we used the daily mobility data aggregated at the county level beside COVID-19 statistics and demographic information for short-term forecasting of COVID-19 outbreaks in the United States. The daily data are fed to a deep learning model based on Long Short-Term Memory (LSTM) to predict the accumulated number of COVID-19 cases in the next two weeks. A significant average correlation was achieved ( r =0.83 ( p = 0.005 )) between the model predicted and actual accumulated cases in the interval from August 1, 2020 until January 22, 2021. The model predictions had r > 0.7 for 87% of the counties across the United States. A lower correlation was reported for the counties with total cases of <1000 during the test interval. The average mean absolute error (MAE) was 605.4 and decreased with a decrease in the total number of cases during the testing interval. The model was able to capture the effect of government responses on COVID-19 cases. Also, it was able to capture the effect of age demographics on the COVID-19 spread. It showed that the average daily cases decreased with a decrease in the retiree percentage and increased with an increase in the young percentage. Lessons learned from this study not only can help with managing the COVID-19 pandemic but also can help with early and effective management of possible future pandemics. The code used for this study was made publicly available on https://github.com/Murtadha44/covid-19-spread-risk.